Bionorm

Hawthorn Extract

Crataegus sp. (Leaf and Flower)≥ 2.5% Hyperoside by spectrophotometry Cardiovascular HealthHawthorn Extract is well known for its anxiolytic, antioxidant and cardiovascular supportive effects. It also provides safe and effective treatment for the early stages of heart disease, angina, myocarditis, arteriosclerosis, nervous conditions like insomnia.The major constituents of this product are flavonoids like hyperoside, vitexin, and rutin that are known to be safe for strengthening blood vessels, vascular insufficiency and blood clots, restoring the heart muscle wall and lowering the heart cholesterol.It can be used as a pharmaceutical ingredient due to the Active Substance Master File and produced appropriate to European Pharmacopeia with a GMP certificate.

Lemon Balm Extract

Melissa officinalis L.(Leaf)≥ 2% Rosmarinic Acid by HPLCLemon Balm Extract is used for its mood uplifting, fever reducing, sedative, anti bacterial, anti-anxiety, spasmolytic and cognitive function booster effects.The natural chemical constituents of this extract are known to be flavonoids (quercitrin, rhamnocitrin) and hydroxycinnamic acids (Rosmarinic acid, caffeic acid). Rather than its sedative and anti-anxiety effects it used to relieve minor gastrointestinal complaints, asthma, coughs, migraine headaches and toothaches.It is produced appropriate to European Pharmacopeia and supplied with an Active Substance Master File with a GMP certificate that enables it to be used as a pharmaceutical ingredient.

Butcher´s Broom Extract

Ruscus aculeatus L. (Root)DER 5-7.5:1Butcher’s Broom Extract is used to treat complaints from chronic venous insufficiency, the heaviness of legs, haemorrhoids, leg cramps, swelling of the legs, the sensation of pain, itching, and burning.The characteristic constituents of butcher’s broom extract are steroidal saponins based upon ruscogenin and neoruscogenin, such as ruscin and ruscoside.By complying with the monograph of the European Pharmacopoeia and being supplied with a GMP certificate and Active Substance Master File, this extract can be used as a pharmaceutical ingredient.

Ivy Leaf Extract

Hedera helix L.(Leaf)≥ 10% Hederacoside C by HPLCThe Ivy Leaf Extract treats respiratory disorders due to its expectorant, emollient, and bronchospasmolytic effects.Hederacoside C and α-hederin, the triterpenoid saponins are the constituents that are known to be rich in this plant. It is generally used in the treatment of cough whereas it can be used to treat acute and chronic inflammatory bronchial disorders.ASMF enables this product which is produced appropriate to European Pharmacopeia, to be used as a pharmaceutical ingredient, whereas the GMP certificate supplied by the Health Ministration guarantees all processes to be tracked until the product.

Passion Flower Extract

Passiflora incarnata L.(Leaf)≥ 1.5% Isovitexin by HPLCPassion Flower Extract is a traditional herbal medicinal product for the relief of mild symptoms of mental stress and mood disorders, along with sleep disorders and temporary insomnia to aid sleep.The extract contains flavones such as isovitexin and vitexin that are known to be the key molecules regarding to the European Pharmacopeia.The ASMF allows this product to be used as a pharmaceutical-grade ingredient, and the Health Ministration’s GMP accreditation ensures its high quality.

Ruscogenins

Ruscus aculeatus L.(Root)≥ 95-103% Ruscogenins By HPLCRuscogenins is a combination of the molecules Ruscogenin and Neoruscogenin. It is used for its anti- elastase, permeability reduction, vasoconstrictive and anti haemorrhoidal properties, and to treat chronic venous insufficiency.The isolated molecule group, Ruscogenins from Ruscus aculeatus, reduces cell permeability through its anti-elastase activity by degrading elastin the main component of the extracellular matrix. Furthermore, in-vivo studies suggest that its vasoconstrictive effect may be mediated by calcium and the alpha-1 adrenergic receptors.This GMP certified pharmaceutical ingredient is supplied with an Active Substance Master File and produced according to European Pharmacopeia.