Bionap

MOROSIL™

Morosil™ is a standardized botanical extract used in nutraceutical applications, particularly in the field of weight management and metabolic health.Key Benefits:• Standardized blood orange extract obtained exclusively from the juice of Moro red oranges (Citrus sinensis (L.) Osbeck), the most pigmented of the Sicilian blood orange cultivars• Grown in the PGI-protected Arancia Rossa di Sicilia zone in eastern Sicily, where volcanic soil and marked day-night temperature swings around Mount Etna drive natural anthocyanin development• Standardized composition (% w/w): anthocyanins as cyanidin-3-glucoside 0.8-0.9%, hydroxycinnamic acids (caffeic, cumaric, sinapic, ferulic, cinnamic) 0.8-1.0%, flavanones (hesperidin, narirutin) 2.0-2.2%, ascorbic acid 4.3-4.5%• Acts on adipocyte metabolism and differentiation via modulation of redox homeostasis and downregulation of adipogenesis-specific transcription factors (PPARγ, C/EBPα, SREBP-1c) and lipogenic enzymes (ACC-α, FAS), supporting a balance between lipogenesis and lipid β-oxidation• Associated with support for fat mass and body composition management, waist and hip circumference, lean mass preservation, and lipid and glycemic metabolic profile• Non-GMO Project Verified, VeganOK, Halal, and Clinically Proven certified; independently verified for identity and purity through Purity-IQ, an ISO/IEC 17025-accredited authenticity testing methodology (NMR and qPCR-based)• Traceable, food-industry co-product sourcing (juice from oranges not meeting fresh-market food standards)• Produced by Bionap (Belpasso, Sicily) and distributed by Safic-Alcan• Shelf life: 36 monthsTypical Applications:Blood orange extract / Moro orange extract / red orange extract for nutraceutical formulations targeting weight management, body composition, fat metabolism, and metabolic health support and indirectly improve cardiovascular functions. Suitable for capsules, tablets, powders, liquid formats, and gummies at the dose of 400 mg/day. Nutraceutical ingredient for weight-management product lines, including formulations addressing pre- and post-GLP-1 treatment nutritional support, and for products positioned on lipid and glycemic metabolic health.

BERGAVIT™

Bergavit™ is a standardized flavonoid extract obtained from bergamot juice (Citrus bergamia), a co-product of essential oil production, cultivated in Calabria, Italy. Developed by Bionap for cardiovascular nutraceutical applications, it is supported by two published clinical studies on lipid metabolism.Key Benefits:• Standardized to 25-28% (w/w) flavonoids (naringin, neoeriocitrin, neohesperidin and derivatives)• Supported by two published human clinical studies: a 6-month open prospective study (Toth et al., 2016, Frontiers in Pharmacology, n=80) and a 4-month randomized double-blind placebo-controlled trial (Spina et al., 2024, Foods, n=64), both showing reductions in LDL and total cholesterol at 150 mg/day of flavonoids• Positioned for cardiovascular support, lipid metabolism balance, and healthy cholesterol level maintenance, relevant to cardiometabolic and cardiovascular wellness formulations• Co-product valorization: bergamot juice is a by-product of bergamot essential oil extraction from the peel, supporting a circular sourcing model• Vegan and Non-GMO Project Verified• Recommended dosage: 150 mg of flavonoids/day, corresponding to 550-600 mg/day of Bergavit™• Produced by Bionap and distributed by Safic-AlcanTypical Applications: Bergamot flavonoid extract / lipid metabolism support ingredient for dietary supplements and nutraceutical formulations targeting cardiovascular wellness, cholesterol balance, and general cardiometabolic health. Suitable for capsule and tablet formats. Complementary ingredient for cardiovascular product lines, including combination formulas with other lipid-metabolism actives.

OXIMMUNE™

Botanical extract designed for food products. It is a solid extract of Sicilian Red orange fruit. Shelf life: 24 months.Benefits:Helps to prevent infection Provides a natural support to the immune system

HYDROVAS™ 10

Botanical extract designed for nutraceutical applications. It contains hydroxytyrosol which is extracted from olive fruits Olea Europaea (L.) using original processes. Shelf life: 36 months.

RED ORANGE COMPLEX™

Botanical extract suitable for food applications. It is a standardized solid powder extract obtained from the juice of three pigmented (Moro, Tarocco and Sanguinello) varieties of Sicilian blood orange grown. Shelf life: 36 months.

ALTILIX™

Botanical extract suitable for nutraceutical applications. It is a solid powder extract obtained from the leaves of a particular cultivar named Cynara cardunculus var. Shelf life: 36 months.Benefits:Supports liver, metabolic & cardiovascular healthHelps in weight management and also decrease intracellular fat accumulation