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IBSIUM®
Provided by Gnosis By Lesaffre
About
ibSium® is a proprietary, patented probiotic yeast strain used in nutraceutical and dietary supplement applications, developed by Lesaffre for digestive comfort and gut balance support.
Key Benefits:
• Registered strain Saccharomyces cerevisiae CNCM I-3856, exclusive to Lesaffre, developed through a dedicated clinical substantiation program
• Positioned for digestive comfort, bloating relief, abdominal comfort, and bowel habit balance, relevant to irritable bowel and functional digestive discomfort formulations
• Yeast-based probiotic format: naturally resistant to gastric acid and bile salts, no encapsulation or protective coating required, unaffected by antibiotic therapy
• Transient, non-colonizing mode of action, supporting a balanced gut microbiota without permanent strain implantation
• US GRAS (FDA 21 CFR §172.896) and EU QPS status, non-GMO, gluten-free, lactose-free, suitable for Kosher, Halal, vegetarian and vegan diets
• High stability: 18 months at ambient temperature, no cold chain required[HJ1.1]
• Available in powders and vermicelli
• Recommended dosage: 4 billion CFU/day (1 to 2 capsules)
• Not recommended for individuals in fragile health conditions (severely immunocompromised individuals, critically ill or extremely premature infants), consistent with standard probiotic yeast precautions[HJ2.1][TU2.2]
• Produced by Gnosis by Lesaffre and distributed by Safic-Alcan
Typical Applications:
Probiotic yeast / digestive comfort probiotic / gut microbiota support ingredient for dietary supplements and nutraceutical formulations targeting occasional digestive discomfort, bloating, irregular transit, and general gut wellness. Suitable for capsules, sachets, and stick pack formats. Complementary ingredient for gut-health product lines, including formulations supporting digestive comfort alongside GLP-1 weight-management treatments, and for combination formulas with complementary probiotic strains such as Lactobacillus rhamnosus GG.
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About gnosis by lesaffre
For over 30 years, Lesaffre has been involved in Human Health & Nutrition as part of its ambition to Better Nourish and Protect the Planet. In November 2018, Lesaffre acquired Gnosis Advanced Biotech and officially combined it with Lesaffre Human Care to form a new Business Unit named Gnosis by Lesaffre. At Gnosis by Lesaffre, we are committed to cultivating and to delivering nutritional actives, probiotics, and nutritional and functional yeasts that benefit human health and wellbeing, thanks to the power of microorganisms and biotransformation processes like fermentation. Put differently, we explore life to improve living. Our vision: At Gnosis by Lesaffre, we strive for a world that moves better, digests better, ages better, feels better, and, ultimately, lives better thanks to microorganisms and biotransformation.
Probiotic Yeast for Digestive Comfort
Ibsium® is a proprietary, patented probiotic yeast strain, registered by Lesaffre as Saccharomyces cerevisiae CNCM I-3856. Developed through a dedicated clinical substantiation programme spanning over a decade, it is positioned within the digestive comfort segment of the nutraceutical market, supporting balanced bowel habits and general gut wellbeing.
As a yeast-based probiotic, Ibsium® differs structurally from bacterial probiotics: its eukaryotic cell wall confers natural resistance to gastric acid and bile salts, allowing it to reach the intestine without protective encapsulation, and leaves it unaffected by concurrent antibiotic therapy. Its action is transient rather than colonizing, supporting the gut’s natural microbial balance without permanently altering the resident microbiota.
Ibsium® is manufactured to consistent quality standards, is Non-GMO, gluten-free, lactose-free, and suitable for Kosher, Halal, vegetarian and vegan formulations, with a shelf life of 18 months at ambient temperature. Available in rod-shape and powder formats, it integrates readily into capsules, sachets, and stick packs.
Falling within the Probiotics & Postbiotics category, Ibsium® is positioned as a science-backed, single-strain yeast ingredient for manufacturers developing digestive comfort, gut microbiota, and general wellness nutraceutical formulations.